SCHEMBL7929166

SCHEMBL7929166

[O-][S+](c1ccc(F)cc1)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
ACHE P22303 1/20 0.32
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18601849 0.81
SCHEMBL7052956 0.78
SCHEMBL7935649 0.78 CA1 (0.31) CA1CA2CA7CA9ACHE
SCHEMBL15391669 0.78 MEN1 (0.38) CA1CA2CA7CA9ACHE
SCHEMBL7940657 0.78 ESR1 (0.39) CA1CA2CA9ACHE
SCHEMBL6760551 0.78 ACHE (0.38) CA1CA2CA7CA9ACHE
SCHEMBL22912676 0.78 ACHE (0.36) CA1CA2CA7CA9ACHE
SCHEMBL17288700 0.78
SCHEMBL7651489 0.78 LMNA (0.38) CA1CA2CA7CA9IDO1
SCHEMBL789123 0.78 CYP2A6 (0.38) CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed