Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11648867 | 0.87 | CA12 (0.62) | GAABRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL21568041 | 0.87 | GAA (0.66) | GAABRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL21551678 | 0.86 | GPR35 (0.59) | GAABRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL90967 | 0.85 | ALDH1A1 (0.59) | GAABRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL11850690 | 0.84 | HPGD (0.70) | GAABRD4TSHRRAB9ACYP1A2 | |
| SCHEMBL1092461 | 0.83 | RAB9A (0.58) | GAABRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL29645247 | 0.83 | HPGD (0.75) | GAABRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL2009980 | 0.83 | MEN1 (0.72) | GAABRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL2308213 | 0.83 | GAA (0.56) | GAABRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL29645245 | 0.83 | HPGD (0.75) | GAABRD4HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078996-A1 | VALUE CHAIN RETURN PROCESS FOR SPENT POLYURETHANES BY HYDROGENATION | BASF SE (DE) | 2022-04-21 | — | — | WO | disclosed |
| WO-2002048898-A1 | METHOD FOR SCREENING FOR INHIBITORS OF ALZHEIMER'S DISEASE | PRANA BIOTECHNOLOGY LIMITED (AU) | 2002-06-20 | — | — | WO | disclosed |
| US-4282368-A | Preparation of p-substituted aromatic carbamic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | disclosed |
| EP-0000815-A1 | Process for preparing N-aryl or N-aralkyl substituted urethanes | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1979-02-21 | — | — | EP | disclosed |