Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867300 | 0.93 | TSHR (0.42) | TSHRKDM4ETDP1USP2MAPT | |
| SCHEMBL3482344 | 0.91 | TSHR (0.41) | TSHRKDM4ETDP1USP2MAPT | |
| SCHEMBL345645 | 0.91 | TSHR (0.41) | TSHRKDM4ETDP1USP2MAPT | |
| SCHEMBL346911 | 0.91 | TSHR (0.41) | TSHRKDM4ETDP1USP2MAPT | |
| SCHEMBL818109 | 0.91 | TSHR (0.41) | TSHRKDM4ETDP1USP2MAPT | |
| SCHEMBL22142455 | 0.86 | TSHR (0.43) | TSHRKDM4ETDP1USP2MAPT | |
| SCHEMBL345647 | 0.86 | THRB (0.39) | TSHRKDM4ETDP1USP2MAPT | |
| SCHEMBL10622476 | 0.85 | TSHR (0.37) | TSHRKDM4ETDP1USP2MAPT | |
| SCHEMBL146689 | 0.84 | TSHR (0.42) | TSHRKDM4ETDP1USP2MAPT | |
| SCHEMBL29362926 | 0.82 | ALDH1A1 (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| US-4155953-A | Process for production of modified polychlorotrifluoroethylene | DAIKIN KOGYO CO., LTD. (JP) | 1979-05-22 | — | — | US | disclosed |