Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649849 | 0.87 | KMT2A (0.55) | MAPTTP53ALDH1A1APPKMT2A | |
| SCHEMBL6651408 | 0.83 | ALDH1A1 (0.48) | MAPTTP53ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7553111 | 0.83 | APP (0.47) | MAPTTP53ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL27463941 | 0.82 | APP (0.46) | MAPTTP53ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7653573 | 0.78 | APP (0.52) | TP53ALDH1A1L3MBTL1APPKMT2A | |
| SCHEMBL7646678 | 0.78 | KMT2A (0.61) | TP53ALDH1A1KDM4EL3MBTL1APP | |
| SCHEMBL6650864 | 0.77 | TP53 (0.51) | MAPTTP53ALDH1A1L3MBTL1APP | |
| SCHEMBL7646312 | 0.77 | APP (0.46) | MAPTTP53ALDH1A1APPKMT2A | |
| SCHEMBL7651874 | 0.76 | ATM (0.46) | MAPTTP53ALDH1A1KDM4EAPP | |
| SCHEMBL7651486 | 0.75 | PRNP (0.50) | MAPTALDH1A1KDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339077-B1 | FOR PROPHYLAXIS OR OF GALLSTONES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-15 | — | — | US | disclosed |