Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654134 | 0.98 | DPP4 (0.33) | CHRNA7CHRNA10CHRNA9PDCD1CD274 | |
| SCHEMBL7653224 | 0.93 | DPP4 (0.34) | PDCD1CD274DPP4PARP1GPR84 | |
| SCHEMBL7650202 | 0.85 | DPP4 (0.36) | PDCD1CD274DPP4PARP1 | |
| SCHEMBL27453595 | 0.81 | LIPG (0.43) | GPR84 | |
| SCHEMBL5541755 | 0.80 | DPP4 (0.48) | CHRNA7CHRNA10CHRNA9PDCD1CD274 | |
| SCHEMBL7653189 | 0.79 | LIPG (0.41) | — | |
| SCHEMBL5548261 | 0.78 | DPP4 (0.50) | PDCD1CD274DPP4 | |
| SCHEMBL7648144 | 0.77 | DPP4 (0.39) | PDCD1CD274DPP4PARP1 | |
| SCHEMBL7650731 | 0.77 | CYP1A2 (0.46) | — | |
| SCHEMBL7654737 | 0.77 | CNR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |