Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314909 | 0.90 | KLK7 (0.49) | KLK7MAPTMEN1KMT2ALMNA | |
| SCHEMBL4534323 | 0.84 | CYP1A2 (0.53) | KLK7LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6934292 | 0.82 | LTA4H (0.45) | MAPK14LTA4HMAPTMEN1KMT2A | |
| SCHEMBL5705855 | 0.79 | GAA (0.47) | MAPK14MAPTMEN1KMT2ALMNA | |
| SCHEMBL27517796 | 0.78 | LTA4H (0.52) | LTA4HMEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL26606686 | 0.76 | ALDH1A1 (0.36) | MAPK14MAPTKMT2ANPSR1NAMPT | |
| SCHEMBL4672007 | 0.76 | LTA4H (0.42) | MAPK14LTA4HMAPTMEN1KMT2A | |
| SCHEMBL1772316 | 0.76 | MMP8 (0.51) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL6154370 | 0.76 | MMP8 (0.51) | MAPTMEN1KMT2ANPSR1NAMPT | |
| SCHEMBL3541681 | 0.76 | MEN1 (0.49) | MEN1KMT2ALMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407120-B1 | ADMINISTERING PYRIDINYLACETAMIDE OR PHENYLACETAMIDE DERIVATIVE TO TREAT CARDIOVASCULAR, EATING, SEXUAL, BRAIN, NERVOUS SYSTEM, GASTROINTESTINAL, UROGENITAL, PSYCHOLOGICAL, AND RESPIRATORY SYSTEM DISORDERS | PFIZER INC. | 2002-06-18 | — | — | US | disclosed |
| EP-1033366-A2 | Amide derivatives useful as Neuropeptide Y (NPY) antagonists | Pfizer Products Inc. (US) | 2000-09-06 | — | — | EP | disclosed |