Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649508 | 1.00 | KMT2A (0.54) | KMT2AMEN1PPARGNCOA2NCOA1 | |
| SCHEMBL7653534 | 0.86 | GPR34 (0.57) | KMT2AMEN1C3AR1ADAMTS5 | |
| SCHEMBL7648460 | 0.84 | C3AR1 (0.53) | KMT2AMEN1C3AR1POLBCASP3 | |
| SCHEMBL7648470 | 0.84 | C3AR1 (0.53) | KMT2AMEN1C3AR1POLBCASP3 | |
| SCHEMBL9752048 | 0.83 | KMT2A (0.57) | KMT2AMEN1PPARGNCOA2NCOA1 | |
| SCHEMBL7859236 | 0.83 | C3AR1 (0.49) | KMT2AMEN1C3AR1CTSDPOLB | |
| SCHEMBL7652741 | 0.82 | C3AR1 (0.44) | KMT2AMEN1C3AR1RECQLRAB9A | |
| SCHEMBL30585604 | 0.81 | MC4R (0.46) | KMT2AMEN1HTTC3AR1RAB9A | |
| SCHEMBL27856688 | 0.81 | MC4R (0.46) | KMT2AMEN1HTTC3AR1RAB9A | |
| Naphthylamine SCHEMBL27915557 | 0.81 | C3AR1 (0.46) | C3AR1TGM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489339-B1 | C3A receptor ligands | SMITHKLINE BEECHAM CORPORATION | 2002-12-03 | — | — | US | claimed |
| EP-1119357-A1 | C3A RECEPTOR LIGANDS | SmithKline Beecham Corporation (US) | 2001-08-01 | — | — | EP | claimed |
| WO-2000009129-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | claimed |
| US-6489339-B1 | C3A receptor ligands | SMITHKLINE BEECHAM CORPORATION | 2002-12-03 | — | — | US | disclosed |
| EP-1119357-A1 | C3A RECEPTOR LIGANDS | SmithKline Beecham Corporation (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000009129-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |