Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 9/20 | 0.57 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651910 | 0.86 | KMT2A (0.54) | C3AR1MEN1KMT2AADAMTS5 | |
| SCHEMBL7649508 | 0.86 | KMT2A (0.54) | C3AR1MEN1KMT2AADAMTS5 | |
| SCHEMBL10277213 | 0.83 | C3AR1 (0.53) | C3AR1 | |
| SCHEMBL4407484 | 0.83 | C3AR1 (0.53) | C3AR1 | |
| SCHEMBL6768020 | 0.80 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL631840 | 0.80 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL5145708 | 0.80 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL10786296 | 0.80 | FOLH1 (0.57) | C3AR1FOLH1 | |
| SCHEMBL10786282 | 0.80 | FOLH1 (0.57) | C3AR1FOLH1 | |
| Hydrochloric Acid SCHEMBL333889 | 0.79 | FOLH1 (0.58) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489339-B1 | C3A receptor ligands | SMITHKLINE BEECHAM CORPORATION | 2002-12-03 | — | — | US | claimed |
| EP-1119357-A1 | C3A RECEPTOR LIGANDS | SmithKline Beecham Corporation (US) | 2001-08-01 | — | — | EP | claimed |
| WO-2000009129-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | claimed |
| US-6489339-B1 | C3A receptor ligands | SMITHKLINE BEECHAM CORPORATION | 2002-12-03 | — | — | US | disclosed |
| EP-1119357-A1 | C3A RECEPTOR LIGANDS | SmithKline Beecham Corporation (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000009129-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |