Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 6/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995613 | 0.90 | PTGS2 (0.40) | BRAFALOX5APFEN1PTGS2PTGS1 | |
| SCHEMBL7001355 | 0.87 | PTGS2 (0.39) | BRAFPTGS2PTGS1 | |
| SCHEMBL6992554 | 0.85 | PTGS2 (0.40) | PTGS2PTGS1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL6994262 | 0.85 | KIF11 (0.37) | BRAFPTGS2PDE3BPDE3APTGS1 | |
| SCHEMBL7001761 | 0.84 | L3MBTL1 (0.38) | BRAFPTGS2PTGS1PIK3CDPIK3CA | |
| SCHEMBL6997793 | 0.82 | PTGS2 (0.40) | BRAFALOX5APFEN1PTGS2PTGS1 | |
| SCHEMBL6994072 | 0.82 | BRAF (0.42) | BRAFPTGS2PTGS1 | |
| SCHEMBL7002132 | 0.82 | BRAF (0.42) | BRAFALOX5APFEN1PTGS2PDE3B | |
| SCHEMBL7002292 | 0.82 | PTGS2 (0.39) | BRAFPTGS2PTGS1PIK3CDPIK3CA | |
| SCHEMBL6998609 | 0.82 | PTGS2 (0.43) | BRAFPTGS2PTGS1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |