Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | AURKA | O14965 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665732 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL7652166 | 0.78 | PTGS2 (0.66) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL6681087 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL28765399 | 0.73 | CHEK1 (0.47) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL6677461 | 0.71 | ALDH1A1 (0.56) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL27834225 | 0.71 | ALDH1A1 (0.56) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL4501557 | 0.71 | ALDH1A1 (0.82) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL4698487 | 0.70 | ALDH1A1 (0.58) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL23402655 | 0.69 | NPC1 (0.47) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL6259170 | 0.69 | CA12 (0.75) | ALDH1A1KDM4EL3MBTL1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117223-A | Hot melt inks containing polyketones | XEROX CORPORATION (US) | 2000-09-12 | — | — | US | claimed |
| CN-1980664-B | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS | 2011-02-23 | — | — | CN | disclosed |
| CN-1980664-A | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS (DK) | 2007-06-13 | — | — | CN | disclosed |
| US-6461417-B1 | Ink compositions | XEROX CORPORATION | 2002-10-08 | — | — | US | disclosed |
| US-6117223-A | Hot melt inks containing polyketones | XEROX CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |