Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642675 | 0.61 | HPGD (0.42) | HPGDNOTUM | |
| SCHEMBL3211485 | 0.58 | HPGD (0.33) | HPGDNOTUM | |
| SCHEMBL12320654 | 0.56 | HPGD (0.42) | HPGDNOTUM | |
| SCHEMBL29351597 | 0.56 | MAOA (0.52) | HPGDNOTUM | |
| SCHEMBL20776999 | 0.56 | NOTUM (0.44) | HPGDNOTUM | |
| SCHEMBL975897 | 0.56 | MAOA (0.52) | HPGDNOTUM | |
| SCHEMBL25138589 | 0.56 | HPGD (0.42) | HPGDNOTUM | |
| SCHEMBL7757572 | 0.56 | AADAT (0.47) | HPGDNOTUM | |
| SCHEMBL19771132 | 0.55 | MAOA (0.45) | HPGDNOTUM | |
| SCHEMBL20383138 | 0.55 | HTR2A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346624-B1 | ENZYME INHIBITORS FORMED BY DEHYDROHALOGENATION | PFIZER INC | 2002-02-12 | — | — | US | disclosed |
| US-6344563-B1 | SULFIDING, DEHYDROHALOGENATION, FORMATION OF BOND BETWEEN CARBON AND NITROGEN | NORRIS TIMOTHY (US) | 2002-02-05 | — | — | US | disclosed |
| US-6239285-B1 | REACTING A TETRAHYDRO-4-(3-(4-FLUOROPHENYL)THIO)PHENYL-2H-PYRAN-4-CARBOXA MIDE WITH HETEROCYCLE RING | PFIZER INC | 2001-05-29 | — | — | US | disclosed |
| CN-1291609-A | Method of preparing 5-lipoxidase inhibitor possessing different heterocyclic ring system | PFIZER PROD INC (US) | 2001-04-18 | — | — | CN | disclosed |
| EP-1081143-A1 | Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems | Pfizer Products Inc. (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1081146-A1 | Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems | Pfizer Products Inc. (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1081144-A2 | Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems | Pfizer Products Inc. (US) | 2001-03-07 | — | — | EP | disclosed |
| CN-1286250-A | Method for preparing 5-lipooxygenase inhibitor having changeable heterocycle system | PFIZER PROD INC (US) | 2001-03-07 | — | — | CN | disclosed |
| CN-1286251-A | Method for preparing 5-lipooxygenase inhibitor having changeable heterocycle system | PFIZER PROD INC (US) | 2001-03-07 | — | — | CN | disclosed |