Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649126 | 0.85 | KMT2A (0.51) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL7800206 | 0.84 | LMNA (0.45) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL10823522 | 0.83 | KMT2A (0.76) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL7652479 | 0.82 | MAPT (0.43) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL9518321 | 0.81 | KMT2A (0.73) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL7997909 | 0.81 | LMNA (0.49) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL6156961 | 0.79 | KMT2A (0.65) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL7653835 | 0.79 | KMT2A (0.52) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL312287 | 0.78 | KMT2A (0.92) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL5836718 | 0.77 | SLC6A2 (0.67) | KMT2ATDP1SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998662-A | O-amino (thio) phenolcarboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-12-07 | — | — | US | claimed |
| EP-0905170-B1 | Polybenzoxazoles and polybenzothiazoles precursors | QIMONDA AG (DE) | 2013-10-30 | — | — | EP | disclosed |
| US-6437178-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH NITRO(THIO)PHENOL; REDUCTION | INFINEON TECHNOLOGIES AG (DE) | 2002-08-20 | — | — | US | disclosed |
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | SIEMENS AKTIENGESELLSCHAFT | 2001-12-27 | — | — | US | disclosed |
| EP-0905124-B1 | o-amino(thio)phenol-carboxylic acids and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| EP-0905123-B1 | o-amino(thio)phenol-carboxylic acids and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6310238-B1 | INTERMEDIATES FOR THE PREPARATION OF POLYBENZOXAZOLES AND POLYBENZOTHIAZOLES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2001-10-30 | — | — | US | disclosed |
| US-6120970-A | Polybenzoxazole and polybenzothiazole precursors | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |
| US-6096921-A | USED FOR THE PREPARATION OF HIGH-TEMPERATURE-STABLE POLYMERS, SUCH AS POLYBENZOXAZOLES AND POLYBENZTHIAZOLES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | disclosed |
| US-5998662-A | O-amino (thio) phenolcarboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-12-07 | — | — | US | disclosed |
| EP-0905124-A1 | o-amino(thio)phenol-carboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | disclosed |
| EP-0905123-A1 | o-amino(thio)phenol-carboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | disclosed |
| EP-0905170-A2 | Polybenzoxazoles and polybenzothiazoles precursors | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | TPMT, PAH, AADAT | KMT2A 985/4885TDP1 3548/4885SLC6A2 2861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.