Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800206 | 0.96 | LMNA (0.45) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7794369 | 0.89 | LMNA (0.41) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7652342 | 0.81 | KMT2A (0.56) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7652479 | 0.77 | MAPT (0.43) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7656023 | 0.77 | MAPT (0.40) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7554986 | 0.77 | BACE1 (0.41) | KMT2AALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL10823522 | 0.74 | KMT2A (0.76) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7649126 | 0.74 | KMT2A (0.51) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7651791 | 0.73 | MAPT (0.40) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL9518321 | 0.73 | KMT2A (0.73) | LMNAKMT2ATDP1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096921-A | USED FOR THE PREPARATION OF HIGH-TEMPERATURE-STABLE POLYMERS, SUCH AS POLYBENZOXAZOLES AND POLYBENZTHIAZOLES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | disclosed |
| US-5998662-A | O-amino (thio) phenolcarboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-12-07 | — | — | US | disclosed |