Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 4/20 | 0.33 |
| ▸ | EDNRB | P24530 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652598 | 0.79 | CA2 (0.44) | ELANECTSGCA2EDNRAEDNRB | |
| SCHEMBL28034970 | 0.76 | CA1 (0.50) | CA2PTPRCEDNRAEDNRBCA12 | |
| SCHEMBL6704515 | 0.74 | PPARA (0.41) | ELANECTSGPPARAALDH1A1 | |
| SCHEMBL3100642 | 0.70 | BCAT2 (0.50) | CA2PTPRCEDNRAEDNRBCA12 | |
| SCHEMBL301797 | 0.70 | CA2 (0.47) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL1164460 | 0.69 | CA2 (0.47) | ELANECTSGCA2EDNRAEDNRB | |
| SCHEMBL5655444 | 0.69 | CA2 (0.42) | CA2CA12CA1CA9SMN1; SMN2 | |
| SCHEMBL27624264 | 0.69 | CA2 (0.44) | ELANECTSGCA2CA12CA1 | |
| Ammonia Solution, Strong SCHEMBL28150872 | 0.68 | CA2 (0.45) | CA2CA12CA1CA9SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL12481385 | 0.68 | CA2 (0.45) | CA2CA12CA1CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432994-B1 | CARDIOVASCULAR DISORDERS, GLAUCOMA; ANTIINFLAMMATORY, WOUND HEALING, HYPOTENSIVE, ANTIASTHMATIC, AND ANTIANAPHYLACTIC AGENTS | TEXAS BIOTECHNOLOGY CORPORATION | 2002-08-13 | — | — | US | disclosed |