Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789668 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL6122390 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL10438567 | 0.77 | ESR1 (0.79) | ESR1TSHRHSD17B10TP53LMNA | |
| SCHEMBL4760306 | 0.76 | NR1H3 (0.61) | ALDH1A1HPGDSMN1; SMN2HSD17B10NR1H3 | |
| SCHEMBL17333403 | 0.75 | ESR1 (0.60) | ESR1TSHRHSD17B10TP53KMT2A | |
| SCHEMBL17333618 | 0.73 | ESR1 (0.58) | ESR1TSHRSMN1; SMN2HSD17B10TP53 | |
| SCHEMBL6122995 | 0.72 | PGR (0.57) | ALDH1A1TSHRSMN1; SMN2POLBMAPT | |
| SCHEMBL7212010 | 0.72 | ALDH1A1 (0.60) | ALDH1A1HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL8224221 | 0.72 | ESR1 (0.75) | ESR1ALDH1A1TSHRHSD17B10TP53 | |
| SCHEMBL5282738 | 0.72 | ALDH1A1 (0.61) | ALDH1A1HPGDTSHRSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432994-B1 | CARDIOVASCULAR DISORDERS, GLAUCOMA; ANTIINFLAMMATORY, WOUND HEALING, HYPOTENSIVE, ANTIASTHMATIC, AND ANTIANAPHYLACTIC AGENTS | TEXAS BIOTECHNOLOGY CORPORATION | 2002-08-13 | — | — | US | disclosed |