Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849610 | 0.76 | LMNA (0.43) | GRM7ROCK2ROCK1POLBLMNA | |
| SCHEMBL6846987 | 0.74 | CCR2 (0.41) | GRM7CCR2CNR1CNR2SIGMAR1 | |
| SCHEMBL6851333 | 0.73 | CCR2 (0.41) | GRM7CCR2CNR1CNR2POLB | |
| SCHEMBL6851432 | 0.66 | P2RX7 (0.38) | CCR2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6849558 | 0.66 | CCR2 (0.41) | CCR2POLBKDM4EALDH1A1MAPT | |
| SCHEMBL25894418 | 0.66 | NPC1 (0.74) | CNR1CNR2POLBLMNAALDH1A1 | |
| SCHEMBL6849769 | 0.65 | CCR2 (0.43) | CCR2LMNAKMT2AMEN1RAB9A | |
| SCHEMBL6846803 | 0.65 | CCR2 (0.41) | CCR2POLBLMNAALDH1A1MAPT | |
| SCHEMBL6849628 | 0.64 | CCR2 (0.41) | CCR2POLBKDM4EALDH1A1MAPT | |
| SCHEMBL2409477 | 0.64 | NPC1 (0.60) | ROCK2ROCK1CNR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020058659-A1 | Imidazole compounds | HIGH POINT PHARMACEUTICALS, LLC | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058659-A1 | Imidazole compounds | HRH3, HRH4, HRH2 | GRM7 654/4885ROCK2 3680/4885ROCK1 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.