Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001085 | 0.74 | PTGS2 (0.42) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL27703349 | 0.74 | KMT2A (0.45) | PTGS1ALDH1A1 | |
| SCHEMBL4962599 | 0.72 | PTGS2 (0.49) | PTGS2PTGS1ABCB11ALDH1A1MT-CO2 | |
| SCHEMBL27930588 | 0.70 | PTGS2 (0.44) | PTGS2PTGS1ABCB11ALDH1A1MT-CO2 | |
| SCHEMBL10300269 | 0.70 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL7677302 | 0.70 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL4713209 | 0.69 | PTGS2 (0.49) | PTGS2PTGS1ABCB11ALDH1A1MT-CO2 | |
| SCHEMBL7005878 | 0.68 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL2376239 | 0.67 | ENPP2 (0.72) | PTGS2 | |
| SCHEMBL6339818 | 0.67 | PTGS2 (0.66) | PTGS2PTGS1ABCB11ALDH1A1MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |