Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 12/20 | 0.41 |
| ▸ | F10 | P00742 | 10/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | C1S | P09871 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7653265 | 0.84 | F2 (0.43) | KMT2AF2F10PRSS1ST14 | |
| SCHEMBL7664428 | 0.83 | F2 (0.47) | KMT2AF2F10PRSS1ST14 | |
| SCHEMBL7679501 | 0.70 | F7 (0.70) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7658493 | 0.68 | F2 (0.52) | F2F10PRSS1 | |
| SCHEMBL7651340 | 0.67 | F2 (0.44) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL537039 | 0.66 | ALDH1A1 (0.49) | — | |
| SCHEMBL7655295 | 0.65 | PLAU (0.58) | KMT2AF2F10PRSS1PRSS2 | |
| SCHEMBL7666062 | 0.65 | PLAU (0.61) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL2778 | 0.65 | TSHR (0.52) | — | |
| SCHEMBL30084385 | 0.65 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |