Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 12/20 | 0.63 |
| ▸ | CSNK2B | P67870 | 12/20 | 0.63 |
| ▸ | CSNK2A1 | P68400 | 12/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.57 |
| ▸ | POLH | Q9Y253 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.57 |
| ▸ | IP6K2 | Q9UHH9 | 4/20 | 0.57 |
| ▸ | TNKS | O95271 | 3/20 | 0.57 |
| ▸ | PARP1 | P09874 | 3/20 | 0.57 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.57 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926335 | 0.84 | GABRP (0.63) | CSNK2A2CSNK2BCSNK2A1CYP3A4MAPT | |
| SCHEMBL7639120 | 0.84 | PLA2G2A (0.59) | CSNK2A2CSNK2BCSNK2A1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL928083 | 0.83 | PLA2G2A (0.58) | CSNK2A2CSNK2BCSNK2A1CYP3A4MAPT | |
| SCHEMBL7637766 | 0.82 | MAPT (0.67) | CSNK2A2CSNK2BCSNK2A1CYP3A4MAPT | |
| SCHEMBL7639939 | 0.82 | NPC1 (0.59) | CSNK2A2CSNK2BCSNK2A1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL926011 | 0.81 | NPC1 (0.58) | CSNK2A2CSNK2BCSNK2A1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL926266 | 0.81 | MAPT (0.64) | CSNK2A2CSNK2BCSNK2A1CYP3A4MAPT | |
| SCHEMBL7643991 | 0.80 | MEN1 (0.58) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH | |
| Hydrochloric Acid SCHEMBL925356 | 0.79 | MEN1 (0.57) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH | |
| SCHEMBL29664594 | 0.78 | ALOX5 (0.78) | CSNK2A2CSNK2BCSNK2A1ALOX5POLH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268628-B1 | 2-ARYL AND 2 -HETEROARYL 4H-1-BENZOPYRAN-4-ONE-6-AMIDINO DERIVATIVES FOR THE TREATMENT OF ARTHRITIS, CANCER AND RELATED PAIN | ROTTAPHARM SPA (IT) | 2012-05-16 | — | — | EP | disclosed |