Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654440 | 0.74 | CYP19A1 (0.56) | CYP19A1HTTSMN1; SMN2 | |
| SCHEMBL16494597 | 0.71 | CYP19A1 (0.53) | CYP19A1 | |
| SCHEMBL2179847 | 0.68 | LIPG (0.42) | HTTSMN1; SMN2 | |
| SCHEMBL9652691 | 0.66 | HSD11B1 (0.45) | — | |
| SCHEMBL9800774 | 0.65 | NR1H2 (0.39) | — | |
| SCHEMBL266417 | 0.64 | LIPG (0.47) | HTTSMN1; SMN2 | |
| SCHEMBL17450350 | 0.63 | CYP19A1 (0.58) | CYP19A1CYP11B1 | |
| SCHEMBL31734211 | 0.63 | LIPG (0.46) | HTTSMN1; SMN2 | |
| SCHEMBL4861353 | 0.63 | PSMB5 (0.49) | SMN1; SMN2 | |
| SCHEMBL28080183 | 0.62 | LIPG (0.42) | HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358984-B1 | FOR THERAPY OF HYPERTENSION AND/OR DISEASES SUCH AS HEART AND RENAL DISEASES | LEAD CHEMICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |