Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MPL | P40238 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119790 | 0.77 | CA2 (0.39) | ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL15352797 | 0.72 | ALDH1A1 (0.35) | ALDH1A1TDP1CTNNB1WNT3AGAA | |
| SCHEMBL15242418 | 0.71 | ALDH1A1 (0.33) | ALDH1A1TDP1CTNNB1WNT3A | |
| SCHEMBL3701609 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TDP1CTNNB1WNT3A | |
| SCHEMBL22591301 | 0.70 | ALDH1A1 (0.35) | ALDH1A1TDP1CTNNB1WNT3AGAA | |
| SCHEMBL15674825 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TDP1CTNNB1WNT3AGAA | |
| SCHEMBL15979644 | 0.70 | ALDH1A1 (0.32) | ALDH1A1TDP1CTNNB1WNT3A | |
| SCHEMBL15352502 | 0.70 | CTNNB1 (0.34) | ALDH1A1TDP1CTNNB1WNT3A | |
| SCHEMBL28783014 | 0.68 | ALDH1A1 (0.33) | ALDH1A1TDP1CTNNB1WNT3A | |
| SCHEMBL599517 | 0.67 | PDE2A (0.32) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | disclosed |
| EP-3686198-B1 | MU-OPIOID RECEPTOR AGONIST AND PREPARATION METHOD THEREFOR AND USE THEREOF IN FIELD OF MEDICINE | SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO LTD (CN) | 2022-12-14 | — | — | EP | disclosed |
| EP-3686198-A1 | mu-OPIOID RECEPTOR AGONIST AND PREPARATION METHOD THEREFOR AND USE THEREOF IN FIELD OF MEDICINE | Shanghai Synergy Pharmaceutical Sciences Co., Ltd (CN) | 2020-07-29 | — | — | EP | disclosed |
| WO-2019052557-A1 | μ-OPIOID RECEPTOR AGONIST AND PREPARATION METHOD THEREFOR AND USE THEREOF IN FIELD OF MEDICINE | 上海华汇拓医药科技有限公司 | 2019-03-21 | — | — | WO | disclosed |
| US-9868719-B2 | Compounds with pesticidal activity | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-16 | — | — | US | disclosed |
| US-9795550-B2 | Gamma-diketones for treatment and prevention of aging skin and wrinkles | SAMUMED, LLC (US) | 2017-10-24 | — | — | US | disclosed |
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-9730447-B2 | Fungicidal amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-08-15 | — | — | US | disclosed |
| US-9730447-B2 | Fungicidal amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2867228-B1 | FUNGICIDAL HETEROCYCLIC CARBOXAMIDES | DU PONT (US) | 2017-07-26 | — | — | EP | disclosed |
| EP-2216332-A1 | 2-Alkyl-cycloalk(en)yl-carboxamides and their use as fungizides | Bayer CropScience AG (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-2098120-A2 | 2-alkyl-cycloalk(en) yl-carboxamides | Bayer CropScience AG (DE) | 2009-09-09 | — | — | EP | disclosed |
| US-20090192172-A1 | 2-Alkyl-Cycloalk(en)yl-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
| US-20090192172-A1 | 2-Alkyl-Cycloalk(en)yl-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | ISHIHARA SANGYO KAISHA LTD (JP) | 2008-12-25 | — | — | US | disclosed |
| CN-101296892-A | PPAR active compounds | PLEXXIKON INC (US) | 2008-10-29 | — | — | CN | disclosed |
| US-7273919-B1 | High heat polyethersulfone compositions | GENERAL ELECTRIC COMPANY (US) | 2007-09-25 | — | — | US | disclosed |
| US-7273919-B1 | High heat polyethersulfone compositions | GENERAL ELECTRIC COMPANY (US) | 2007-09-25 | — | — | US | disclosed |
| US-20070219344-A1 | HIGH HEAT POLYETHERSULFONE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2007-09-20 | — | — | US | disclosed |
| US-20070219344-A1 | HIGH HEAT POLYETHERSULFONE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192172-A1 | 2-Alkyl-Cycloalk(en)yl-Carboxamides | DCXR, CYCS, MRPL21 | ALDH1A1 1840/4885TDP1 2762/4885CTNNB1 4096/4885 |
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | AADAC, NAT1, TH | ALDH1A1 1277/4885TDP1 2547/4885CTNNB1 3551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.