Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 6/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11217882 | 0.88 | GAA (0.44) | SLC10A2GAAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL6762248 | 0.78 | MAPT (0.39) | SLC10A2GAAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL6762383 | 0.78 | MAPT (0.39) | SLC10A2GAAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL6947116 | 0.76 | PDGFRB (0.41) | GAAALDH1A1ALOX15HSD17B10MAPT | |
| SCHEMBL7652710 | 0.74 | SLC10A2 (0.40) | SLC10A2SRCGAAALDH1A1PDE4A | |
| SCHEMBL6762661 | 0.72 | PKM (0.45) | GAAALDH1A1ALOX15HSD17B10MAPT | |
| SCHEMBL6766348 | 0.72 | SLC10A2 (0.46) | SLC10A2GAAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL10755196 | 0.72 | PDE3B (0.53) | ALDH1A1HSD17B10MAPTCYP3A4PDE3B | |
| SCHEMBL7015217 | 0.70 | PDGFRB (0.46) | SLC10A2GAAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL28114292 | 0.68 | TUBB4A (0.47) | SLC10A2GAAALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417194-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | PFIZER, INC. | 2002-07-09 | — | — | US | disclosed |
| US-6048864-A | Quinolines and quinazolines useful in therapy | PFIZER INC (US) | 2000-04-11 | — | — | US | disclosed |
| EP-0887344-A1 | Quinolines and quinazolines useful in therapy | Pfizer Limited (GB) | 1998-12-30 | — | — | EP | disclosed |