Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.41 |
| ▸ | FNTB | P49356 | 3/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 6/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653580 | 0.87 | FNTA (0.44) | FNTAFNTBCYP51A1PTGS2 | |
| SCHEMBL7653575 | 0.84 | PTGS2 (0.37) | FNTAFNTBCYP51A1PTGS2CYP3A4 | |
| SCHEMBL7656299 | 0.81 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL7654320 | 0.81 | FNTA (0.53) | FNTAFNTB | |
| SCHEMBL7658747 | 0.80 | FNTA (0.46) | FNTAFNTBCYP51A1PTGS2CYP3A4 | |
| SCHEMBL7668699 | 0.80 | FNTA (0.51) | FNTAFNTB | |
| SCHEMBL7660388 | 0.80 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL7660347 | 0.79 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL7658756 | 0.79 | FNTA (0.49) | FNTAFNTBCYP51A1CYP3A4CYP2C19 | |
| SCHEMBL7669307 | 0.75 | FNTA (0.45) | FNTAFNTBCYP51A1PTGS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410539-B1 | ANTICARCINOGENIC AGENTS | ASTRAZENCA UK LIMITED (GB) | 2002-06-25 | — | — | US | claimed |