Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218995 | 0.92 | MEN1 (0.54) | B3GNT2ALDH1A1CYP2C9SMN1; SMN2MEN1 | |
| SCHEMBL6231298 | 0.91 | RXFP1 (0.50) | B3GNT2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7017776 | 0.90 | PPARA (0.47) | TRPV1EPHX2NR1H4B3GNT2ALDH1A1 | |
| SCHEMBL7021536 | 0.87 | B3GNT2 (0.45) | EPHX2NR1H4B3GNT2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6233923 | 0.86 | NAMPT (0.46) | B3GNT2ALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL6239501 | 0.85 | MEN1 (0.56) | NR1H4B3GNT2ALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL7624469 | 0.85 | MEN1 (0.50) | B3GNT2ALDH1A1CYP2C9SMN1; SMN2MEN1 | |
| SCHEMBL6237603 | 0.84 | MMP13 (0.50) | ALDH1A1HPGDCYP2C9CYP2D6MEN1 | |
| SCHEMBL6234083 | 0.84 | MEN1 (0.53) | B3GNT2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6466931 | 0.83 | MEN1 (0.54) | B3GNT2ALDH1A1CYP2C9SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | MMP13, MMP9, MMP3 | TRPV1 4074/4885EPHX2 1678/4885NR1H4 2332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.