Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653632 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EPKMMAPTCNR2 | |
| SCHEMBL7114558 | 0.86 | ABCC9 (0.53) | ALDH1A1KDM4EPKMMAPTCNR2 | |
| SCHEMBL7114555 | 0.86 | ABCC9 (0.53) | ALDH1A1KDM4EPKMMAPTCNR2 | |
| SCHEMBL7109500 | 0.85 | LY96 (0.58) | ALDH1A1KDM4EPKMMAPTCA1 | |
| SCHEMBL7109497 | 0.85 | LY96 (0.58) | ALDH1A1KDM4EPKMMAPTCA1 | |
| SCHEMBL6364338 | 0.84 | NLRP3 (0.53) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL7666426 | 0.83 | MAPT (0.48) | ALDH1A1KDM4EPKMMAPTCNR2 | |
| SCHEMBL7666432 | 0.83 | MAPT (0.48) | ALDH1A1KDM4EPKMMAPTCNR2 | |
| SCHEMBL7659572 | 0.82 | MAPT (0.62) | ALDH1A1KDM4EPKMMAPTLMNA | |
| SCHEMBL7659576 | 0.82 | MAPT (0.62) | ALDH1A1KDM4EPKMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350778-B1 | CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-02-26 | — | — | US | disclosed |