Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655440 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL7550093 | 0.89 | PPARD (0.33) | ROCK2GRIN1L3MBTL1MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL7655186 | 0.87 | PTGDR2 (0.32) | GRIN1MAPT | |
| Hydrochloric Acid SCHEMBL7658632 | 0.87 | PTGDR2 (0.32) | GRIN1MAPT | |
| SCHEMBL7548916 | 0.86 | GRIN1 (0.32) | ROCK2GRIN1L3MBTL1MAPT | |
| SCHEMBL7548639 | 0.84 | MTNR1A (0.32) | ROCK2GRIN1L3MBTL1 | |
| SCHEMBL7547391 | 0.83 | MAPT (0.33) | L3MBTL1MAPTTDP1 | |
| SCHEMBL7549043 | 0.82 | MTNR1A (0.33) | ROCK2L3MBTL1MAPTTDP1 | |
| SCHEMBL7550462 | 0.81 | MTNR1A (0.32) | ROCK2L3MBTL1 | |
| SCHEMBL7549035 | 0.81 | MTNR1A (0.36) | L3MBTL1MAPTNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495587-B1 | TREATING A DAMAGE TO THE CENTRAL NERVOUS SYSTEM INDUCED BY AN ISCHEMIC OR HYPOXIC CONDITION AND STROKE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-12-17 | — | — | US | disclosed |