Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652636 | 0.98 | PTGDR2 (0.38) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7654023 | 0.98 | NAAA (0.35) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7652944 | 0.97 | NAAA (0.37) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7652615 | 0.95 | NAAA (0.36) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7648243 | 0.93 | PTGDR2 (0.39) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7650684 | 0.87 | SLC6A2 (0.38) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL5544918 | 0.86 | PTGDR2 (0.41) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7650825 | 0.81 | SIGMAR1 (0.38) | SLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL11278522 | 0.80 | CYSLTR2 (0.49) | SLC6A2SLC6A4HTR1DHTR1BCYSLTR2 | |
| SCHEMBL7648876 | 0.80 | SIGMAR1 (0.40) | SLC6A4PTGDR2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |