Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652944 | 0.98 | NAAA (0.37) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7653710 | 0.98 | NAAA (0.36) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7652636 | 0.97 | PTGDR2 (0.38) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7652615 | 0.93 | NAAA (0.36) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7648243 | 0.92 | PTGDR2 (0.39) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL7650684 | 0.86 | SLC6A2 (0.38) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL5544918 | 0.84 | PTGDR2 (0.41) | NAAASLC6A2SLC6A4SLC6A3PTGDR2 | |
| SCHEMBL28076276 | 0.82 | CYSLTR2 (0.49) | SLC6A2SLC6A4CYSLTR2CYSLTR1HTR1D | |
| SCHEMBL11278522 | 0.82 | CYSLTR2 (0.49) | SLC6A2SLC6A4CYSLTR2CYSLTR1HTR1D | |
| SCHEMBL7654475 | 0.81 | SIGMAR1 (0.39) | SLC6A2SLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149214-C | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | ������������ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |