Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649502 | 0.88 | MEN1 (0.47) | KMT2AMEN1MC4RPLK1MAPT | |
| SCHEMBL7653005 | 0.88 | TSHR (0.40) | KMT2AMEN1CHRM2ADRA2ACYP2D6 | |
| SCHEMBL7649539 | 0.83 | RAD52 (0.46) | KMT2AMEN1CHRM2CHRM1HTR2A | |
| SCHEMBL610303 | 0.82 | DRD3 (0.43) | KMT2AMEN1OPRM1DRD3HTR7 | |
| SCHEMBL7649700 | 0.80 | LMNA (0.59) | KMT2AMEN1MC4RPOLBHTR7 | |
| SCHEMBL7653795 | 0.79 | SIGMAR1 (0.52) | MC4RCYP2D6SLC6A3MAPT | |
| SCHEMBL7650018 | 0.79 | OGA (0.44) | KMT2AMEN1HTR2AHRH1POLB | |
| SCHEMBL7648589 | 0.78 | POLB (0.48) | KMT2AMEN1CYP2D6POLB | |
| SCHEMBL7646697 | 0.78 | ALDH1A1 (0.57) | KMT2AMEN1POLBMAPT | |
| SCHEMBL7649345 | 0.78 | CYP1A2 (0.44) | CYP2D6POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237887-A1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-11 | — | — | EP | claimed |
| WO-2001029028-A1 | 9- (PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-26 | — | — | WO | claimed |