Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 5/20 | 0.41 |
| ▸ | EDNRB | P24530 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534597 | 0.86 | EDNRA (0.41) | EDNRAEDNRB | |
| SCHEMBL8627743 | 0.82 | EDNRA (0.40) | EDNRAEDNRB | |
| SCHEMBL7814457 | 0.79 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL7653068 | 0.78 | EDNRA (0.51) | EDNRAEDNRB | |
| SCHEMBL7659711 | 0.76 | NPC1 (0.41) | EDNRAEDNRB | |
| SCHEMBL7748131 | 0.76 | NPC1 (0.41) | EDNRAEDNRB | |
| SCHEMBL9543742 | 0.75 | EDNRA (0.49) | EDNRAEDNRB | |
| SCHEMBL7651503 | 0.75 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL7651495 | 0.75 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL9543747 | 0.73 | EDNRA (0.48) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355813-B1 | INTERMEDIATES USEFUL IN PREPARING THESE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2002-03-12 | — | — | US | disclosed |