Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626957 | 0.91 | EDNRA (0.43) | EDNRAEDNRB | |
| SCHEMBL7814457 | 0.89 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL9543742 | 0.84 | EDNRA (0.49) | EDNRAEDNRB | |
| SCHEMBL6953835 | 0.80 | EDNRA (0.45) | EDNRAEDNRB | |
| SCHEMBL8476509 | 0.76 | EDNRA (0.47) | EDNRAEDNRB | |
| SCHEMBL7533979 | 0.73 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL7653814 | 0.73 | EDNRA (0.41) | EDNRAEDNRB | |
| SCHEMBL8626955 | 0.73 | CYP3A4 (0.42) | EDNRAEDNRB | |
| SCHEMBL7534597 | 0.73 | EDNRA (0.41) | EDNRAEDNRB | |
| SCHEMBL8622694 | 0.73 | EDNRA (0.51) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993008799-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-13 | — | — | WO | disclosed |