SCHEMBL765402

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL753666	0.86	LIPG (0.47)	CREBBPLMNAMAPTALDH1A1HTT
	SCHEMBL755691	0.78	NPSR1 (0.41)	LMNAMAPTALDH1A1HTTSMN1; SMN2
	SCHEMBL16921556	0.78	KDM4A (0.40)	KLKB1GRM2
	SCHEMBL751844	0.78	GPBAR1 (0.41)	HTTGRM2RAB9A
	SCHEMBL752814	0.76	CNR2 (0.44)	ALDH1A1
	SCHEMBL2779143	0.74	NPSR1 (0.39)	LMNAMAPTALDH1A1MAPK1SMN1; SMN2
	SCHEMBL27285952	0.74	LMNA (0.55)	CREBBPLMNAMAPTALDH1A1HTT
	SCHEMBL752989	0.73	SMN1; SMN2 (0.42)	LMNAALDH1A1SMN1; SMN2RAB9ANPC1
	SCHEMBL754559	0.73	LIPG (0.35)	MAPTALDH1A1HSD17B10
	SCHEMBL16908924	0.73	NPSR1 (0.35)	LMNAMAPTALDH1A1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.