Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658659 | 0.84 | HRH3 (0.68) | HRH3RAB9AOPRM1OPRK1NPFFR1 | |
| SCHEMBL7654584 | 0.83 | HRH3 (0.60) | HRH3RAB9AOPRM1OPRK1NPFFR1 | |
| SCHEMBL7655725 | 0.82 | HRH3 (0.66) | HRH3RAB9AOPRM1OPRK1NPFFR1 | |
| SCHEMBL7654001 | 0.81 | HRH3 (0.64) | HRH3L3MBTL1 | |
| SCHEMBL7659427 | 0.81 | HRH3 (0.67) | HRH3RAB9AOPRM1OPRK1NPFFR1 | |
| SCHEMBL7656135 | 0.79 | HRH3 (0.67) | HRH3L3MBTL1 | |
| SCHEMBL7663832 | 0.79 | HRH3 (0.66) | HRH3OPRM1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL7656338 | 0.79 | HRH3 (0.66) | HRH3OPRM1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL7654067 | 0.78 | HRH3 (0.60) | HRH3OPRM1OPRK1NPFFR1NPFFR2 | |
| SCHEMBL7666593 | 0.78 | HRH3 (0.71) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002085861-A1 | IMIDAZOLIDINE COMPOUNDS AND THEIR USE AS CXCR3 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6469002-B1 | COMPOUNDS WHICH MODULATE CHEMOKINE RECEPTOR ACTIVITY AND ARE USEFUL IN TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. | 2002-10-22 | — | — | US | disclosed |