Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.68 |
| ▸ | NPFFR1 | Q9GZQ6 | 4/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663832 | 0.93 | HRH3 (0.66) | HRH3NPFFR1NPFFR2OPRM1OPRK1 | |
| SCHEMBL7666593 | 0.91 | HRH3 (0.71) | HRH3OPRL1TSHR | |
| SCHEMBL7654048 | 0.84 | HRH3 (0.68) | HRH3NPFFR1NPFFR2OPRM1OPRK1 | |
| SCHEMBL7655725 | 0.82 | HRH3 (0.66) | HRH3NPFFR1NPFFR2OPRM1OPRK1 | |
| SCHEMBL7659427 | 0.81 | HRH3 (0.67) | HRH3NPFFR1NPFFR2OPRM1OPRK1 | |
| SCHEMBL7669477 | 0.80 | HRH3 (0.49) | HRH3TSHR | |
| SCHEMBL7666194 | 0.79 | HRH3 (0.47) | HRH3 | |
| SCHEMBL7656338 | 0.79 | HRH3 (0.66) | HRH3NPFFR1NPFFR2OPRM1OPRK1 | |
| SCHEMBL7654067 | 0.78 | HRH3 (0.60) | HRH3NPFFR1NPFFR2OPRM1OPRK1 | |
| SCHEMBL7654584 | 0.78 | HRH3 (0.60) | HRH3NPFFR1NPFFR2OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495569-B1 | CHEMOKINE ANTAGONISTS; TREATING DISEASE ASSOCIATED WITH INFLAMMATION AND/OR PATHOGENIC LEUKOCYTE RECRUITMENT AND/OR ACTIVATION | MILLENNIUM PHARMACEUTICALS, INC. | 2002-12-17 | — | — | US | disclosed |