SCHEMBL7654147

SCHEMBL7654147

Cc1cccc(C(=O)NO)c1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.54
TAS1R1 Q7RTX1 2/20 0.54
TAS1R2 Q8TE23 2/20 0.54
HDAC8 Q9BY41 2/20 0.47
MMP3 P08254 1/20 0.47
KDM4E B2RXH2 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 2/20 0.47
MPO P05164 1/20 0.47
HIF1A Q16665 1/20 0.47
ALDH1A1 P00352 2/20 0.44
NPC1 O15118 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
P2RX7 Q99572 3/20 0.43
HDAC6 Q9UBN7 1/20 0.43
ITGB1 P05556 1/20 0.42
ITGA4 P13612 1/20 0.42
POLB P06746 1/20 0.42
HPGD P15428 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7981657 0.85 TAS1R3 (0.54) TAS1R3TAS1R1TAS1R2KDM4ESMN1; SMN2
SCHEMBL31547716 0.85 TAS1R3 (0.54) TAS1R3TAS1R1TAS1R2KDM4ESMN1; SMN2
SCHEMBL16080763 0.83 TAS1R3 (0.52) TAS1R3TAS1R1TAS1R2KDM4ESMN1; SMN2
SCHEMBL10513885 0.82 PTGS2 (0.51) GAAMPOHIF1AHPGDLMNA
SCHEMBL13841435 0.80 TAS1R3 (0.50) TAS1R3TAS1R1TAS1R2KDM4ESMN1; SMN2
SCHEMBL27406399 0.80 TAS1R3 (0.54) TAS1R3TAS1R1TAS1R2ALDH1A1P2RX7
SCHEMBL27885983 0.80 TSHR (0.61) TAS1R3TAS1R1TAS1R2HDAC8MMP3
SCHEMBL6671895 0.80 NPC1 (0.51) TAS1R3TAS1R1TAS1R2HDAC8MMP3
SCHEMBL23070440 0.79 KMT2A (0.48) TAS1R3TAS1R1TAS1R2KDM4ESMN1; SMN2
SCHEMBL4815209 0.79 HPGD (0.62) HDAC8MMP3KDM4ESMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6489490-B1 PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-12-03 US disclosed