Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137519 | 0.88 | RIPK1 (0.37) | RIPK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL14387379 | 0.82 | MAPK1 (0.59) | RIPK1ALDH1A1MAPK1HCAR2ADRA2B | |
| SCHEMBL464725 | 0.81 | HCAR2 (0.45) | ALDH1A1TSHRHCAR2ADRA2BADRA2A | |
| SCHEMBL11659192 | 0.80 | TSHR (0.39) | RIPK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL11237759 | 0.80 | TSHR (0.39) | RIPK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL3099790 | 0.79 | RIPK1 (0.37) | RIPK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL21433903 | 0.79 | RIPK1 (0.37) | RIPK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL8388174 | 0.79 | ALDH1A1 (0.37) | RIPK1ALDH1A1MAPK1HCAR2 | |
| SCHEMBL11966010 | 0.77 | RIPK1 (0.42) | RIPK1MAPK1HCAR2ADRA2BCACNA1F | |
| Isopropylbenzene SCHEMBL2522337 | 0.77 | RIPK1 (0.42) | RIPK1ALDH1A1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117142915-A | Method for synthesizing organic peroxy compound by decarboxylation of carboxylic acid under catalysis of visible light | 中国人民大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-110317131-B | Method for preparing ketone compound from ethylbenzene compound | 内蒙古民族大学 | 2022-02-01 | — | — | CN | disclosed |
| US-20120289749-A1 | Gold Nanocatalysts and Methods of Use Thereof | ASEFA TEWODROS (US) | 2012-11-15 | — | — | US | disclosed |
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289749-A1 | Gold Nanocatalysts and Methods of Use Thereof | SOD1, HCCS, CAT | RIPK1 4218/4885ALDH1A1 169/4885TSHR 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.