Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635884 | 0.84 | ATP4A (0.44) | ATP4AATP4BLMNAL3MBTL1AR | |
| Hydrochloric Acid SCHEMBL15974091 | 0.82 | ATP4A (0.43) | ATP4AATP4BLMNAL3MBTL1AR | |
| SCHEMBL7654186 | 0.79 | TSHR (0.38) | LMNAL3MBTL1KMT2ASMN1; SMN2MAPT | |
| Phenylacetaldehyde SCHEMBL452558 | 0.76 | LMNA (0.44) | LMNAL3MBTL1SIGMAR1KMT2ASMN1; SMN2 | |
| Ethylene Glycol SCHEMBL10990240 | 0.74 | TSHR (0.37) | LMNAKMT2ASMN1; SMN2MAPTRAB9A | |
| Phenylacetaldehyde SCHEMBL1412189 | 0.73 | LMNA (0.41) | LMNAL3MBTL1SIGMAR1KMT2ASMN1; SMN2 | |
| SCHEMBL4918898 | 0.73 | LMNA (0.55) | LMNAL3MBTL1KDM4EMAPT | |
| Propionaldehyde SCHEMBL28820483 | 0.72 | MAPT (0.43) | ATP4AATP4BLMNAL3MBTL1AR | |
| SCHEMBL7654314 | 0.71 | AR (0.35) | ATP4AATP4BL3MBTL1ARKDM4E | |
| Phenylacetaldehyde SCHEMBL10892064 | 0.71 | LMNA (0.39) | LMNAL3MBTL1KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365616-B1 | TRANSPLANT REJECTION | SENTRON MEDICAL, INC. | 2002-04-02 | — | — | US | disclosed |
| EP-1112072-A2 | METHIMAZOLE DERIVATIVES AND TAUTOMERIC CYCLIC THIONES TO TREAT AUTOIMMUNE DISEASES | Sentron Medical, Inc. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000012175-A2 | METHIMAZOLE DERIVATIVES AND TAUTOMERIC CYCLIC THIONES TO TREAT AUTOIMMUNE DISEASES | SENTRON MEDICAL, INC. (US) | 2000-03-09 | — | — | WO | disclosed |