Phenylacetaldehyde

Phenylacetaldehyde

SCHEMBL452558

CCOC(C)OCC.O=CCc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
TAAR1 Q96RJ0 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAOB P27338 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 2/20 0.37
TP53 P04637 1/20 0.37
HTT P42858 1/20 0.36
AOX1 Q06278 1/20 0.36
SLC6A2 P23975 2/20 0.35
SIGMAR1 Q99720 2/20 0.35
MAOA P21397 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
CYP2A6 P11509 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
EPHX1 P07099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylacetaldehyde SCHEMBL1412189 0.96 LMNA (0.41) LMNATAAR1MEN1KMT2AL3MBTL1
Phenylacetaldehyde SCHEMBL10892064 0.93 LMNA (0.39) LMNATAAR1MEN1KMT2AL3MBTL1
Phenylacetaldehyde SCHEMBL17267409 0.91 TSHR (0.38) LMNATAAR1MEN1KMT2AL3MBTL1
Phenylacetaldehyde SCHEMBL112416 0.89 TSHR (0.40) LMNATAAR1MEN1KMT2AL3MBTL1
Dihydrocinnamaldehyde SCHEMBL598211 0.84 SMN1; SMN2 (0.41) LMNATAAR1MEN1KMT2AL3MBTL1
Phenylacetaldehyde SCHEMBL872936 0.84 TRPA1 (0.37) LMNATAAR1MEN1KMT2AL3MBTL1
SCHEMBL8417662 0.84 LMNA (0.43) LMNATAAR1MEN1KMT2AL3MBTL1
SCHEMBL7949742 0.82 TSHR (0.42) LMNATAAR1MEN1KMT2AL3MBTL1
SCHEMBL4865476 0.82 SMN1; SMN2 (0.43) LMNATAAR1MEN1KMT2ASMN1; SMN2
Phenylacetaldehyde SCHEMBL217860 0.81 TAAR1 (0.43) TAAR1MEN1KMT2AL3MBTL1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 725 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2844065-B1 LURE COMPOSITION ATTRATEC GMBH (DE) 2021-01-06 EP claimed
WO-2011147455-A1 FLAVORING SUBSTANCE-INCLUDED COMPOUNDS SYMRISE AG (DE) 2011-12-01 WO claimed
US-20080233056-A1 ORGANOLEPTIC COMPOUNDS WITH ENHANCED PROPERTIES ZYMES, LLC (US) 2008-09-25 US claimed
WO-2008116021-A1 ORGANOLEPTIC COMPOUNDS WITH ENHANCED PROPERTIES ZYMES, LLC (US) 2008-09-25 WO claimed
EP-1311525-A2 COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION Inspire Pharmaceuticals, Inc. (US) 2003-05-21 EP claimed
US-20030036489-A1 Consumable composition comprising perfumed particles and article containing the same THE PROCTER & GAMBLE COMPANY 2003-02-20 US claimed
WO-2002090479-A1 PERFUMED PARTICLES AND ARTICLES CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
US-20020052337-A1 Composition and method for inhibiting platelet aggregation NORTH CAROLINA, UNIVERSITY OF 2002-05-02 US claimed
WO-2002016381-A2 COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION INSPIRE PHARMACEUTICALS, INC. (US) 2002-02-28 WO claimed
EP-0676388-B1 Process for the preparation of phenylacetic acid derivatives and intermediate products BAYER AG (DE) 1999-07-14 EP claimed
US-5756858-A Process for the preparation of substituted phenylacetic acid derivatives and novel intermediates BAYER AKTIENGESELLSCHAFT (DE) 1998-05-26 US claimed
US-12630783-B2 Muguet type fragrance compounds SYMRISE AG (DE) 2026-05-19 US disclosed
US-12630781-B2 Fragrance or flavour mixture SYMRISE AG (DE) 2026-05-19 US disclosed
EP-4192614-B1 PROCESS FOR THE PREPARATION OF MICROCAPSULES SYMRISE AG (DE) 2026-05-06 EP disclosed
US-12583833-B2 Enrichment of a diastereomer in Magnolan SYMRISE AG (DE) 2026-03-24 US disclosed
US-4459224-A Perfume compositions as well as perfumed articles and materials containing alkyl substituted benzyl cyanides as a fragrance NAARDEN INTERNATIONAL N.V. (NL) 1984-07-10 US disclosed
EP-0040894-B1 PERFUME COMPOSITIONS AND PERFUMED ARTICLES CONTAINING ESTERS OF SUBSTITUTED BICYCLO (2.2.1)HEPTANE- AND HEPTENE-CARBOXYLIC ACIDS AS PERFUME BASE NAARDEN INTERNATIONAL N.V. (NL) 1984-01-25 EP disclosed
US-4421689-A Derivatives of 1,5-dimethylbicyclo [3,2,1] octane, the preparation of these compounds and their use as perfume compound SHELL ITERNATIONAL RESEARCH MAATSCHAPPIJ B.V., THE NETHERLANDS A COMPANY OF THE NETHERLANDS (NL) 1983-12-20 US disclosed
US-4218348-A PERFUMES SHELL OIL COMPANY (US) 1980-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583833-B2 Enrichment of a diastereomer in Magnolan TRPA1, ENO1, ADH1A LMNA 1005/4885TAAR1 593/4885MEN1 28/4885
US-12630783-B2 Muguet type fragrance compounds MGAT1, RFT1, CPT1A LMNA 938/4885TAAR1 1204/4885MEN1 1286/4885
US-12630781-B2 Fragrance or flavour mixture NOTUM, FFAR2, FFAR1 LMNA 1289/4885TAAR1 249/4885MEN1 4045/4885
US-20080233056-A1 ORGANOLEPTIC COMPOUNDS WITH ENHANCED PROPERTIES SQLE, COQ8B, COQ8A LMNA 476/4885TAAR1 2325/4885MEN1 951/4885
US-20020052337-A1 Composition and method for inhibiting platelet aggregation P2RY11, P2RY12, P2RY13 LMNA 3019/4885TAAR1 1020/4885MEN1 2541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.