Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798769 | 0.89 | KDM4E (0.46) | CNR2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL30537733 | 0.89 | KDM4E (0.46) | CNR2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7655901 | 0.87 | CNR2 (0.40) | CNR2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7653475 | 0.83 | CNR2 (0.39) | CNR2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL11050977 | 0.82 | CNR2 (0.45) | CNR2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7654737 | 0.82 | CNR2 (0.38) | CNR2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7653729 | 0.81 | CNR2 (0.39) | CNR2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7653189 | 0.80 | LIPG (0.41) | CNR2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL321423 | 0.79 | ADRA2B (0.39) | KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7653734 | 0.78 | CYP1A2 (0.56) | CNR2KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |