Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380508 | 0.83 | CPA3 (0.46) | EPORFFAR1 | |
| SCHEMBL7647484 | 0.74 | KMT2A (0.38) | FFAR1MEN1KMT2APTGFR | |
| SCHEMBL3380552 | 0.72 | HDAC1 (0.49) | FFAR1MAPT | |
| SCHEMBL365336 | 0.70 | FFAR1 (0.70) | FFAR1FFAR4MEN1KMT2AEPHX1 | |
| Hydrochloric Acid SCHEMBL30765594 | 0.69 | FFAR1 (0.68) | FFAR1FFAR4MEN1KMT2AEPHX1 | |
| SCHEMBL14026865 | 0.68 | FFAR4 (0.56) | FFAR1FFAR4MEN1KMT2AEPHX1 | |
| SCHEMBL1981615 | 0.68 | FFAR4 (0.59) | FFAR1FFAR4MEN1KMT2AEPHX1 | |
| SCHEMBL4445391 | 0.68 | TAAR1 (0.56) | FFAR1FFAR4MEN1KMT2AEPHX1 | |
| SCHEMBL31273982 | 0.67 | HTR2A (0.60) | FFAR1MEN1KMT2AEPHX1PPARG | |
| SCHEMBL3470487 | 0.67 | HTR2A (0.60) | FFAR1MEN1KMT2AEPHX1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002514184-A | — | — | 2002-05-14 | — | — | JP | claimed |
| EP-1005348-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1998013046-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | claimed |