Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29706640 | 1.00 | KMO (0.64) | KMOHDAC8MAPTTDP1ERCC5 | |
| SCHEMBL21173955 | 0.90 | KMO (0.68) | KMOMAPTTDP1CA12CA1 | |
| SCHEMBL29287804 | 0.89 | MAPT (0.63) | KMOHDAC8MAPTTDP1ERCC5 | |
| Biphenyl SCHEMBL7862554 | 0.87 | F2 (0.61) | KMOMAPTTDP1NPC1RAB9A | |
| SCHEMBL23044716 | 0.86 | KMO (0.62) | KMOHDAC8MAPTTDP1ERCC5 | |
| SCHEMBL27687572 | 0.86 | KMO (0.53) | KMOHDAC8MAPTTDP1ERCC5 | |
| Biphenyl SCHEMBL6058549 | 0.85 | PARP1 (0.52) | KMOMAPTERCC5FEN1NPC1 | |
| Biphenyl SCHEMBL7934686 | 0.85 | KMO (0.47) | KMOHDAC8MAPTTDP1ERCC5 | |
| SCHEMBL545343 | 0.85 | LMNA (0.58) | MAPTTDP1RAB9ALMNA | |
| SCHEMBL6300562 | 0.84 | KMO (0.51) | KMOHDAC8MAPTTDP1ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114573811-A | Imide slurry, synthesis method thereof and composition containing imide slurry | 宁波博雅聚力新材料科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-113881225-A | Imide film and synthetic method thereof | 宁波博雅聚力新材料科技有限公司 | 2022-01-04 | — | — | CN | disclosed |
| EP-1007032-A4 | 4-CYANO-4-DEFORMYLSORDARICIN DERIVATIVES | MERCK & CO INC (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1007032-A1 | 4-CYANO-4-DEFORMYLSORDARICIN DERIVATIVES | Merck & Co., Inc. (US) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999009975-A1 | 4-CYANO-4-DEFORMYLSORDARICIN DERIVATIVES | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | disclosed |