Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488019 | 0.94 | CA12 (0.59) | CA12CA1CA2CA9LMNA | |
| SCHEMBL3345207 | 0.85 | CA12 (0.68) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8378142 | 0.83 | LMNA (0.62) | CA12CA1CA2CA9LMNA | |
| SCHEMBL6955671 | 0.83 | LMNA (0.62) | CA12CA1CA2CA9LMNA | |
| SCHEMBL6955675 | 0.83 | LMNA (0.62) | CA12CA1CA2CA9LMNA | |
| SCHEMBL23417613 | 0.82 | CA12 (0.64) | CA12CA1CA2CA9LMNA | |
| SCHEMBL28357053 | 0.82 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL21923314 | 0.82 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL10223234 | 0.82 | CA12 (0.68) | CA12CA1CA2CA9MAPT | |
| SCHEMBL28353130 | 0.80 | CA12 (0.55) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465483-B1 | TREATING OR PREVENTING STROKES; CHRONIC INFLAMMATORY DISORDERS SUCH AS BRONCHIAL ASTHMA AND ARTHRITIS; ANTIPROLIFERATIVE EFFECT; ULCERATIVE COLITIS AND CROHN'S DISEASE | BOEHRINGER INGELHEIM GMBH (DE) | 2002-10-15 | — | — | US | disclosed |
| US-5607943-A | CARDIOPROTECTIVE, CEREBROPROTECTIVE, ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1997-03-04 | — | — | US | disclosed |