Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654597 | 0.94 | CA12 (0.63) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3345207 | 0.81 | CA12 (0.68) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8635713 | 0.81 | LMNA (0.53) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL901614 | 0.80 | CA12 (0.73) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6955675 | 0.80 | LMNA (0.62) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8378142 | 0.80 | LMNA (0.62) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6955671 | 0.80 | LMNA (0.62) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL23417613 | 0.79 | CA12 (0.64) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL21923314 | 0.79 | CA12 (0.57) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8428854 | 0.79 | ALDH1A1 (0.61) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925650-A | PROTECTION AGAINST STROKE IN MAMMALS | BOEHRINGER INGELHEIM KG (DE) | 1999-07-20 | — | — | US | disclosed |
| US-5837712-A | PREVENTION OF STROKE | BOEHRINGER INGELHEIM KG (DE) | 1998-11-17 | — | — | US | disclosed |