Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345207 | 0.86 | CA12 (0.68) | LMNACA12CA1CA2CA9 | |
| SCHEMBL8378142 | 0.84 | LMNA (0.62) | LMNACA12CA1CA2CA9 | |
| SCHEMBL6955675 | 0.84 | LMNA (0.62) | LMNACA12CA1CA2CA9 | |
| SCHEMBL7654597 | 0.83 | CA12 (0.63) | LMNACA12CA1CA2CA9 | |
| SCHEMBL11807890 | 0.82 | ALDH1A1 (0.65) | LMNACA12CA1CA2CA9 | |
| SCHEMBL23417613 | 0.81 | CA12 (0.64) | LMNACA12CA1CA2CA9 | |
| SCHEMBL15970734 | 0.81 | LMNA (0.61) | LMNACA12CA1CA2CA9 | |
| SCHEMBL20542124 | 0.80 | LMNA (0.60) | LMNACA12CA1CA2CA9 | |
| SCHEMBL20542122 | 0.80 | LMNA (0.60) | LMNACA12CA1CA2CA9 | |
| SCHEMBL8488019 | 0.80 | CA12 (0.59) | LMNACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |