Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | PARP1 | P09874 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29934330 | 0.98 | ATM (0.55) | ATMNPSR1PRMT5LMNAKDM4E | |
| SCHEMBL21381322 | 0.98 | ATM (0.55) | ATMNPSR1PRMT5LMNAKDM4E | |
| SCHEMBL8686734 | 0.76 | PARP1 (0.51) | ATMNPSR1PRMT5LMNAKDM4E | |
| SCHEMBL1032659 | 0.76 | PRMT5 (0.60) | ATMNPSR1PRMT5LMNAKDM4E | |
| SCHEMBL26732566 | 0.75 | PRMT5 (0.46) | ATMNPSR1PRMT5PARP1ALDH1A1 | |
| SCHEMBL1904310 | 0.75 | ATM (0.73) | ATMNPSR1LMNAKDM4EPOLB | |
| SCHEMBL29363334 | 0.75 | ATM (0.73) | ATMNPSR1LMNAKDM4EPOLB | |
| SCHEMBL555280 | 0.74 | ATM (0.57) | ATMNPSR1PRMT5LMNAPOLB | |
| SCHEMBL8808348 | 0.74 | ATM (0.57) | ATMNPSR1PRMT5LMNAKDM4E | |
| SCHEMBL9766383 | 0.74 | ATM (0.57) | ATMNPSR1PRMT5LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4307898-A1 | COMPOSITIONS AND METHODS FOR DECONTAMINATION OF SURFACES | Aviraban, LLC (US) | 2024-01-24 | — | — | EP | claimed |
| CN-107082764-B | Polyhydroxyl phthalazinone compounds, preparation method and application | 上海锐聚恩新药研发有限公司 | 2018-11-02 | — | — | CN | claimed |
| CN-107082764-A | Polyhydroxyl phthalazinone compounds, its preparation method and application | 上海锐聚恩新药研发有限公司 | 2017-08-22 | — | — | CN | claimed |
| US-20050033050-A1 | Phthalazinones and the use thereof in order to combat undesirable microorganisms | BAYER CROPSCIENCE AG (DE) | 2005-02-10 | — | — | US | claimed |
| EP-1430035-A1 | PHTHALAZINONES AND THE USE THEREOF IN ORDER TO COMBAT UNDESIRABLE MICROORGANISMS | Bayer CropScience AG (DE) | 2004-06-23 | — | — | EP | claimed |
| WO-2003024938-A1 | PHTHALAZINONES AND THE USE THEREOF IN ORDER TO COMBAT UNDESIRABLE MICROORGANISMS | BAYER CROPSCIENCE AG (DE) | 2003-03-27 | — | — | WO | claimed |
| CN-107082764-B | Polyhydroxyl phthalazinone compounds, preparation method and application | 上海锐聚恩新药研发有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-107082764-B | Polyhydroxyl phthalazinone compounds, preparation method and application | 上海锐聚恩新药研发有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-107082764-A | Polyhydroxyl phthalazinone compounds, its preparation method and application | 上海锐聚恩新药研发有限公司 | 2017-08-22 | — | — | CN | disclosed |
| CN-107082764-A | Polyhydroxyl phthalazinone compounds, its preparation method and application | 上海锐聚恩新药研发有限公司 | 2017-08-22 | — | — | CN | disclosed |
| US-9278098-B2 | Substituted phthalazines for inducing insulin secretion and protecting beta-cells | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-03-08 | — | — | US | disclosed |
| US-9278098-B2 | Substituted phthalazines for inducing insulin secretion and protecting beta-cells | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-03-08 | — | — | US | disclosed |
| US-20150164892-A1 | LISOFYLLINE ANALOGS AND METHODS FOR USE | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2015-06-18 | — | — | US | disclosed |
| WO-2007027719-A2 | LISOFYLLINE ANALOGUES AND THEIR PHARMEACUETICAL USES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2007-03-08 | — | — | WO | disclosed |
| US-20050033050-A1 | Phthalazinones and the use thereof in order to combat undesirable microorganisms | BAYER CROPSCIENCE AG (DE) | 2005-02-10 | — | — | US | disclosed |
| EP-1430035-A1 | PHTHALAZINONES AND THE USE THEREOF IN ORDER TO COMBAT UNDESIRABLE MICROORGANISMS | Bayer CropScience AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003024938-A1 | PHTHALAZINONES AND THE USE THEREOF IN ORDER TO COMBAT UNDESIRABLE MICROORGANISMS | BAYER CROPSCIENCE AG (DE) | 2003-03-27 | — | — | WO | disclosed |
| CN-1202800-A | Herbicidal composition | NOVARTIS AG (CH) | 1998-12-23 | — | — | CN | disclosed |
| CN-1144526-A | Thiazolidines and oxazolidines substituted by pyridine ring and their use a hypoglycemic agents | NISSAN CHEMICAL IND LTD (JP) | 1997-03-05 | — | — | CN | disclosed |
| US-4112080-A | INSECTICIDE, MITICIDE, NEMATOCIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164892-A1 | LISOFYLLINE ANALOGS AND METHODS FOR USE | IAPP, RNASE1, CTSA | ATM 1855/4885NPSR1 1246/4885PRMT5 3241/4885 |
| US-20050033050-A1 | Phthalazinones and the use thereof in order to combat undesirable microorganisms | PGLS, DCXR, C5 | ATM 3646/4885NPSR1 209/4885PRMT5 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.