Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | LSS | P48449 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682080 | 0.83 | LSS (0.54) | LSSKDM4EGBA1HSD11B1ALDH1A1 | |
| SCHEMBL6974183 | 0.82 | LSS (0.76) | LSSLMNAHSD17B10NPSR1HTT | |
| SCHEMBL7662005 | 0.82 | HTR7 (0.49) | HTR7HTR6LSSLMNACHRM4 | |
| SCHEMBL6975619 | 0.80 | LSS (0.62) | LSSLMNAKDM4EHSD17B10GBA1 | |
| SCHEMBL9514839 | 0.78 | GBA1 (0.65) | LSSKDM4EGBA1HSD11B1NPSR1 | |
| SCHEMBL6980932 | 0.75 | LSS (0.77) | LSSNPSR1ALDH1A1 | |
| SCHEMBL9517357 | 0.75 | LSS (0.55) | LSSLMNAGBA1HSD11B1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7652417 | 0.74 | HRH4 (0.46) | HSD17B10 | |
| Hydrochloric Acid SCHEMBL7654208 | 0.72 | HRH4 (0.49) | LSSCHRM4GPBAR1HSD17B10MAPT | |
| SCHEMBL6977537 | 0.72 | LSS (0.93) | LSSLMNAKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |