Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657257 | 0.90 | LSS (0.52) | LMNASMN1; SMN2HTTTPSAB1KDM4E | |
| SCHEMBL7650545 | 0.82 | CNR1 (0.64) | LMNASMN1; SMN2NPSR1USP2HTT | |
| SCHEMBL7654703 | 0.82 | HTR7 (0.56) | HTR7HTR6LMNANPSR1HTT | |
| SCHEMBL6981479 | 0.79 | CNR1 (0.59) | SMN1; SMN2NPSR1USP2HTTLSS | |
| SCHEMBL7660934 | 0.76 | LSS (0.48) | LMNASMN1; SMN2TSHRHTTTPSAB1 | |
| SCHEMBL7682080 | 0.73 | LSS (0.54) | TSHRKDM4ELSSALDH1A1MEN1 | |
| SCHEMBL8124161 | 0.71 | F10 (0.69) | HTR7HTR6TPSAB1 | |
| SCHEMBL6975859 | 0.69 | LSS (0.71) | NPSR1TSHRLSSALDH1A1 | |
| SCHEMBL3648943 | 0.69 | GPR119 (0.55) | KMT2A | |
| SCHEMBL7662786 | 0.68 | LSS (0.53) | HTR7HTR6TPSAB1LSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |