Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HTR1E | P28566 | 2/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649404 | 0.83 | HTR1E (0.70) | SLC6A3SLC6A2LMNATSHRTDP1 | |
| SCHEMBL15966790 | 0.75 | SLC6A3 (0.64) | SLC6A3SLC6A2SLC6A4DHFRLMNA | |
| SCHEMBL12904188 | 0.74 | SLC6A3 (0.70) | SLC6A3SLC6A2SLC6A4DHFRLMNA | |
| SCHEMBL14906223 | 0.74 | SLC6A3 (0.70) | SLC6A3SLC6A2SLC6A4DHFRLMNA | |
| SCHEMBL17084398 | 0.74 | SLC6A3 (1.00) | SLC6A3SLC6A2SLC6A4DHFRLMNA | |
| SCHEMBL6099068 | 0.73 | SLC6A3 (0.78) | SLC6A3SLC6A2SLC6A4DHFRLMNA | |
| SCHEMBL14453321 | 0.73 | SLC6A3 (0.78) | SLC6A3SLC6A2SLC6A4DHFRLMNA | |
| SCHEMBL12550069 | 0.73 | SLC6A3 (0.78) | SLC6A3SLC6A2SLC6A4DHFRLMNA | |
| SCHEMBL20850913 | 0.73 | SLC6A3 (0.78) | SLC6A3SLC6A2SLC6A4DHFRLMNA | |
| SCHEMBL1462581 | 0.73 | SLC6A3 (0.78) | SLC6A3SLC6A2SLC6A4DHFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407120-B1 | ADMINISTERING PYRIDINYLACETAMIDE OR PHENYLACETAMIDE DERIVATIVE TO TREAT CARDIOVASCULAR, EATING, SEXUAL, BRAIN, NERVOUS SYSTEM, GASTROINTESTINAL, UROGENITAL, PSYCHOLOGICAL, AND RESPIRATORY SYSTEM DISORDERS | PFIZER INC. | 2002-06-18 | — | — | US | disclosed |
| EP-1033366-A2 | Amide derivatives useful as Neuropeptide Y (NPY) antagonists | Pfizer Products Inc. (US) | 2000-09-06 | — | — | EP | disclosed |