Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.39 |
| ▸ | PGR | P06401 | 5/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753714 | 0.86 | OPRM1 (0.44) | NR3C1PGRARRORC | |
| SCHEMBL751911 | 0.82 | RORC (0.43) | NR3C1RORC | |
| SCHEMBL751636 | 0.78 | NR3C1 (0.42) | NR3C1PGRAR | |
| SCHEMBL2896278 | 0.76 | NR3C1 (0.47) | NR3C1PGRAR | |
| SCHEMBL764287 | 0.76 | MAPK1 (0.42) | — | |
| SCHEMBL752588 | 0.74 | KMT2A (0.43) | NR3C1PGRARRORC | |
| SCHEMBL10198841 | 0.70 | SLC6A2 (0.48) | NR3C1PGRAR | |
| SCHEMBL1363138 | 0.70 | NR3C1 (0.48) | NR3C1 | |
| SCHEMBL1362269 | 0.68 | NR3C1 (0.64) | NR3C1 | |
| SCHEMBL12592391 | 0.67 | MEN1 (0.47) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078015-B1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1 AND/OR NF-KAPPAB ACTIVITY AND USE THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2012-03-21 | — | — | EP | disclosed |