Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078920 | 1.00 | LMNA (0.39) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL8460844 | 0.83 | GAA (0.41) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL5597826 | 0.83 | GAA (0.41) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL6544654 | 0.82 | SMN1; SMN2 (0.42) | LMNAHTTNPC1RAB9APKM | |
| SCHEMBL7205062 | 0.82 | LMNA (0.40) | LMNAL3MBTL1MAPTCYP2C19NPC1 | |
| SCHEMBL7205061 | 0.82 | LMNA (0.40) | LMNAL3MBTL1MAPTCYP2C19NPC1 | |
| SCHEMBL2045476 | 0.82 | TSHR (0.44) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL2045474 | 0.82 | TSHR (0.44) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL7651351 | 0.77 | CES1 (0.48) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL7805644 | 0.77 | CES1 (0.48) | LMNAL3MBTL1MAPK1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420362-B1 | Azines containing the 5,6-di-hydro-(1,4,2) dioxazine-3-yl group and the use thereof as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| US-6410600-B1 | CONTROLLING MICROORGANISMS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-25 | — | — | US | disclosed |
| EP-1023275-A1 | AZINES CONTAINING THE 5,6-DI-HYDRO-(1,4,2) DIOXAZINE-3-YL GROUP AND THE USE THEREOF AS FUNGICIDES | BAYER AG (DE) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999019311-A1 | AZINES CONTAINING THE 5,6-DI-HYDRO-(1,4,2) DIOXAZINE-3-YL GROUP AND THE USE THEREOF AS FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-04-22 | — | — | WO | disclosed |